Eccrine Systems is working to provide personal drug response profiles for use by prescribers.
Our foremost efforts involve the development of non-invasive wearable biosensors that enable derivation of personal drug response profiles based on changing drug and biomarker levels in locally stimulated sweat.
The emergent field of pharmacoeccrinology goes beyond pharmacogenetic predictions to actually knowing the drug response of each patient after a drug is administered.
Sweat derived from eccrine glands in human skin contains valuable information about physiological performance and dysfunction. Sweat holds great promise as the best non-invasive source for real-time trending and analysis of molecular biomarkers that can be directly correlated with blood biomarkers, and other gold standard references, and translated into meaningful results and actionable information.
The ability to monitor sweat biomarkers with chronological accuracy is the key to attaining market-enabling improvements in the predictive value of non-invasive wearables data -- across a wide spectrum of applications for medicine, industry, and sport.
Realizing the Promise
Serious applications for medicine, industry, and sport demand analytical accuracy and market-enabling predictive values that have been validated in on-body studies. Multiple biotechnology challenges must be overcome to improve the actionable value of sweat molecular data:
Biosensor specificity, sensitivity, stability, and longevity
Controlling for variability in sweat rate
Sweat stimulation during periods of low availability
Minimizing the influence of external factors
Statistically valid correlations to systemic physiological function and dysfunction
Our modular Sweatronics® platform has been designed to maximize the reuse and integration of proven materials and components, while enabling the rapid innovation and customization of specialized sweat sensor systems for a wide array of medical, industrial, and sport applications.
We have exclusively licensed, and continue to expand, a pioneering IP portfolio that encompasses the design, function, and use of advanced sweat sensor technologies across a broad spectrum of applications.