Personal drug response profiles based on the changing drug and biomarker levels excreted in locally stimulated sweat via a
cost-effective, non-invasive wearable device
Eccrine Systems has demonstrated that a small molecule drug excreted in locally stimulated sweat exhibits pharmacokinetics correlated with blood. PK data from locally stimulated sweat will enable a disruptive innovation that addresses one of the foremost medical challenges of our time... optimized personal pharmacotherapy.
Key Technologies and Know-How:
Physiology and pharmacology of drugs and biomarkers in sweat
Localized sweat stimulation
Electrochemical aptamer-based biosensors (reagentless, washless, continuous sensing)
Sweat bioinformatics and related correlation algorithms
Extensive, multi-dimensional IP portfolio with broad-based claims
Eccrine has demonstrated that a small molecule drug exhibits PK values in locally stimulated sweat consistent with published blood PK values and interpersonal variability.