Personal drug response profiles based on the changing drug and biomarker levels excreted in locally stimulated sweat via a 
cost-effective, non-invasive wearable device


Eccrine Systems has demonstrated that a small molecule drug excreted in locally stimulated sweat exhibits pharmacokinetics correlated with blood. PK data from locally stimulated sweat will enable a disruptive innovation that addresses one of the foremost medical challenges of our time... optimized personal pharmacotherapy.

Key Technologies and Know-How:

 
  • Physiology and pharmacology of drugs and biomarkers in sweat

  • Localized sweat stimulation

  • Microfluidics management

  • Electrochemical aptamer-based biosensors (reagentless, washless, continuous sensing)

  • Sweat bioinformatics and related correlation algorithms

  • Extensive, multi-dimensional IP portfolio with broad-based claims

 
IMG_0809.jpg

Eccrine has demonstrated that a small molecule drug exhibits PK values in locally stimulated sweat consistent with published blood PK values and interpersonal variability.